![]() Provide more accurate predictive models of mutant protein function. TO THE AUTO - MUTE SUITE OF PREDICTORS.Ĭombined power of computational mutagenesis using a four body,Ĭutting-edge machine learning methodologies and tools, to For the remaining two Perl programs, each has only one such line that requires identical editing. ![]() ", and change them to "open(RESULT, 'java -cp weka.jar. Within each of the stability_changes_XX.pl files, scroll midway to find four lines starting with "open(RESULT, 'java. Alternatively, make the following simple edits to five Perl scripts (three programs named stability_changes_XX.pl, as well as activity_ and human_) in the unzipped directory after opening them in any text editor (e.g., Wordpad). The unzipped AutoMute2 folder contains the file weka.jar, to which the computer's CLASSPATH environment variable must point (requires advanced computer skills). ![]() ![]() All versions require Perl (with CPAN library), Java, and internet access (for automatic PDB file downloads) Cygwin users should first download and install Qhull from the online package list. Platform-specific downloads available for PC ( AutoMute2.zip), Mac ( ), and Cygwin ( cygwin_).
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